Articles with "xcr1" as a keyword



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XCR1+ conventional dendritic cell-induced CD4+ T helper 1 cell activation exacerbates cardiac remodeling after ischemic myocardial injury.

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Published in 2023 at "Journal of molecular and cellular cardiology"

DOI: 10.2139/ssrn.4201283

Abstract: Cardiac remodeling has no established therapies targeting inflammation. CD4+ T-cell subsets have been reported to play significant roles in healing process after ischemic myocardial injury, but their detailed mechanisms of activation remain unknown. To explore… read more here.

Keywords: cell; xcr1; cardiac remodeling; activation ... See more keywords
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Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1127485

Abstract: A single population of interferon-regulatory factor 8 (Irf8)-dependent conventional dendritic cell (cDC type1) is considered to be responsible for both immunogenic and tolerogenic responses depending on the surrounding cytokine milieu. Here, we challenge this concept… read more here.

Keywords: cdc1 cluster; cell; cdc1; conventional dendritic ... See more keywords