NR4A1 Exerts Pro-Tumor Role in Glioblastoma via Inducing xCT/GPX4-Regulated Ferroptosis.
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DOI: 10.1002/acn3.70173
Abstract: PURPOSE This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor… read more here.
Keywords: xct; xct gpx4; ferroptosis; tumor ... See more keywords