xCT/SLC7A11 antiporter function inhibits HIV-1 infection.
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DOI: 10.1016/j.virol.2021.01.008
Abstract: Human macrophages are protected by intrinsic antiviral defenses that provide moderate protection against HIV-1 infection. Macrophages that do become infected can serve as long-lived reservoirs, to disseminate HIV-1 to CD4+ T cells. Infection of macrophages… read more here.
Keywords: hiv infection; xct; xct slc7a11; antiporter ... See more keywords