Infection control, genetic assessment of drug resistance and drug susceptibility testing in the current management of multidrug/extensively-resistant tuberculosis (M/XDR-TB) in Europe: A tuberculosis network European Trialsgroup (TBNET) study.
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DOI: 10.1016/j.rmed.2017.09.007
Abstract: AIM Europe has the highest documented caseload and greatest increase in multidrug and extensively drug-resistant tuberculosis (M/XDR-TB) of all World Health Organization (WHO) regions. This survey examines how recommendations for M/XDR-TB management are being implemented.… read more here.
Keywords: tbnet; infection control; drug; tuberculosis ... See more keywords
Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?
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DOI: 10.1080/14787210.2018.1483240
Abstract: ABSTRACT Introduction: The octapeptins are a family of cyclic lipopeptides first reported in the 1970s then largely ignored. At the time, their reported antibiotic activity against polymyxin-resistant bacteria was a curiosity. Today, the advent of… read more here.
Keywords: xdr bacteria; resistant xdr; drug; extensively drug ... See more keywords
Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa
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DOI: 10.1099/mgen.0.000815
Abstract: Extensively drug-resistant tuberculosis (XDR-TB), defined as resistance to at least isoniazid (INH), rifampicin (RIF), a fluoroquinolone (FQ) and a second-line injectable drug (SLID), is difficult to treat and poses a major threat to TB control.… read more here.
Keywords: xdr; transmission; mtb; resistance ... See more keywords
Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins
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DOI: 10.1128/mbio.00105-18
Abstract: ABSTRACT Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi, the causative agent of typhoid. Multidrug-resistant (MDR) isolates are prevalent in parts of Asia and Africa and are often associated with the dominant… read more here.
Keywords: typhi; typhi clone; resistance; antibiotic resistance ... See more keywords
Comparative Genome Analysis of an Extensively Drug-Resistant Isolate of Avian Sequence Type 167 Escherichia coli Strain Sanji with Novel In Silico Serotype O89b:H9
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DOI: 10.1128/msystems.00242-18
Abstract: E. coli strain Sanji is the first sequenced and analyzed genome of the recently emerged pathogenic XDR strains with sequence type ST167 and novel in silico serotype O89b:H9. Comparison of the genomes of Sanji with… read more here.
Keywords: xdr; coli; o89b; coli strain ... See more keywords
O07.5 The index case’s partnership status is important in predicting the likelihood of persistence of introduced XDR NG among MSM
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DOI: 10.1136/sextrans-2019-sti.144
Abstract: Background Extensively drug resistant (XDR) Neisseria gonorrhoeae (NG) strains have recently been isolated in the UK and Australia. We use a mathematical model to assess the importance of the index cases’ partnership status in predicting… read more here.
Keywords: introduced xdr; index; index cases; index case ... See more keywords
Impact of the revised definition of extensively drug-resistant tuberculosis
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DOI: 10.1183/13993003.00641-2021
Abstract: Recently, the World Health Organization (WHO) has released a revised definition of extensively drug-resistant (XDR) tuberculosis (TB) that should be used for clinical and surveillance purposes starting from 1 January, 2021 [1, 2]. The previous… read more here.
Keywords: definition; definition extensively; drug; tuberculosis ... See more keywords
Extensively drug-resistant tuberculosis in the penitentiary facilities of the Russian Federation
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DOI: 10.1183/13993003.congress-2018.pa3683
Abstract: Objective: Of the total number of cases notified in prisons in the WHO European Region, almost ¾ cases of tuberculosis (newly diagnosed and relapses) are registered in the penitentiary facilities of the Russian Federation. Extensively… read more here.
Keywords: russian federation; treatment; tuberculosis; penitentiary facilities ... See more keywords
Treatment outcomes of patients with multidrug-resistant and extensively drug resistant tuberculosis in Hunan Province, China
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DOI: 10.1186/s12879-017-2662-8
Abstract: BackgroundThe worldwide emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has posed additional challenges for global tuberculosis (TB) control efforts, as limited treatment options are available and treatment outcomes are often sub-optimal. This… read more here.
Keywords: treatment outcomes; mdr; treatment; tuberculosis ... See more keywords
Association of extensively drug resistant salmonella infection in children with typhoid fever
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DOI: 10.12669/pjms.38.7.5868
Abstract: Objectives: In resource limited countries facing a huge burden of multidrug resistant and extensively drug resistant (XDR) enteric fever, treatment is a great challenge on the part of a patient as well as a health… read more here.
Keywords: fever; salmonella infection; xdr; association ... See more keywords
Epidemiology, susceptibility, and risk factors for acquisition of MDR/XDR Gram-negative bacteria among kidney transplant recipients with urinary tract infections
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DOI: 10.2147/idr.s163979
Abstract: Background Multiple drug resistant/extensively drug resistant (MDR/XDR) Gram-negative urinary tract infections (UTIs) represent a growing threat to kidney transplant recipients. This retrospective study aimed to assess the incidence and microbiological profile of MDR/XDR Gram-negative UTIs,… read more here.
Keywords: gram negative; mdr xdr; xdr gram; xdr ... See more keywords