Analytical performance of the Xpert MTB/XDR® assay for tuberculosis and expanded resistance detection.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2021.115397
Abstract: In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The… read more here.
Keywords: xpert mtb; xdr assay; mtb xdr; resistance detection ... See more keywords
Diagnostics and new treatment regimens for TB: can the Xpert MTB/XDR assay fill the gap for fluoroquinolone testing?
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00643-25
Abstract: ABSTRACT Rapid diagnosis of resistance-conferring mutations to antibiotics used for the treatment of tuberculosis (TB) is critical for patient care and public health control efforts. Prior guidelines included the use of fluoroquinolones (FQs) for the… read more here.
Keywords: treatment; resistance; xdr assay; drug ... See more keywords