Chemical Pretreatment Activated a Plastic State Amenable to Direct Lineage Reprogramming
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.865038
Abstract: Somatic cells can be chemically reprogrammed into a pluripotent stem cell (CiPSC) state, mediated by an extraembryonic endoderm- (XEN-) like state. We found that the chemical cocktail applied in CiPSC generation initially activated a plastic… read more here.
Keywords: lineage; activated plastic; xen like; cell ... See more keywords