Exendin‐4(Lys27PAL)/gastrin/xenin‐8‐Gln: A novel acylated GLP‐1/gastrin/xenin hybrid peptide that improves metabolic status in obese‐diabetic (ob/ob) mice
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DOI: 10.1002/dmrr.3106
Abstract: Therapeutic benefits of peptide‐based drugs is limited by rapid renal elimination. read more here.
Keywords: gastrin; exendin lys27pal; gastrin xenin; lys27pal gastrin ... See more keywords
Characterisation and antidiabetic utility of a novel hybrid peptide, exendin‐4/gastrin/xenin‐8‐Gln
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.07.027
Abstract: ABSTRACT Enteroendocrine derived hormones such as glucagon‐like‐peptide‐1 (GLP‐1), glucose‐dependent insulinotropic polypeptide (GIP), gastrin and xenin are known to exert complementary beneficial metabolic effects in diabetes. This study has assessed the biological activity and therapeutic utility… read more here.
Keywords: xenin; xenin gln; exendin gastrin; gastrin xenin ... See more keywords