Xenobiotic and endobiotic handling by the mucosal immune system.
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Gastroenterology"
DOI: 10.1097/mog.0000000000000478
Abstract: PURPOSE OF REVIEW Mucosal immune cells in the intestinal tract are continuously exposed to a barrage of both foreign and endogenously generated metabolites, termed xenobiotics, and endobiotics, respectively. This review summarizes recent insights into the… read more here.
Keywords: xenobiotics endobiotics; mucosal; immune system; xenobiotic endobiotic ... See more keywords
The Role of Sulfotransferases in Liver Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.120.000074
Abstract: The cytosolic sulfotransferases (SULTs) are phase II conjugating enzymes that catalyze the transfer of a sulfonate group from the universal sulfate donor 3′-phosphoadenosine-5′-phosphosulfate to a nucleophilic group of their substrates to generate hydrophilic products. Sulfation… read more here.
Keywords: xenobiotics endobiotics; liver diseases; sulfotransferases liver; receptor ... See more keywords