A zebrafish xenograft model for studying human cancer stem cells in distant metastasis and therapy response.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2016.10.009
Abstract: Lethal and incurable bone metastasis is one of the main causes of death in multiple types of cancer. A small subpopulation of cancer stem/progenitor-like cells (CSCs), also known as tumor-initiating cells from heterogenetic cancer is… read more here.
Keywords: cancer; xenograft model; cancer stem; metastasis ... See more keywords
Antitumor effects of flavopiridol, a cyclin-dependent kinase inhibitor, on human cholangiocarcinoma in vitro and in an in vivo xenograft model
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e01675
Abstract: Flavopiridol, a pan-cyclin-dependent kinase (CDK) inhibitor, was recently identified as an effective antitumor agent for several cancers. We investigated the antitumor effect of flavopiridol on cholangiocarcinoma (CCA), in vitro and in vivo. A methylthiotetrazole assay… read more here.
Keywords: flavopiridol; cyclin dependent; vitro vivo; xenograft model ... See more keywords
Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.06.007
Abstract: &NA; Non‐small cell lung cancer (NSCLC) is one of the most common malignant tumors, with a high mortality rate due to the elevated risk of resistance. Natural cucurbitacins and their derivatives are recognized as promising… read more here.
Keywords: xenograft model; treatment; combined therapy; lung cancer ... See more keywords
Simultaneous inhibition of Chk1 and Bcl-xL induces apoptosis in vitro and represses tumour growth in an in vivo xenograft model.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemotherapy"
DOI: 10.1080/1120009x.2022.2125749
Abstract: We previously showed that prexasertib, a checkpoint kinase 1 (Chk1) inhibitor, and navitoclax, a Bcl-2 and Bcl-xL inhibitor, induced a synergistic inhibitory effect on cell proliferation in vitro. Here, we investigated the effect of the simultaneous… read more here.
Keywords: xenograft model; inhibition chk1; chk1 bcl; chk1 ... See more keywords
Active Vitamin D3 (Calcitriol) Increases Adipose Graft Retention in a Xenograft Model.
Sign Up to like & getrecommendations! Published in 2023 at "Aesthetic surgery journal"
DOI: 10.1093/asj/sjad001
Abstract: BACKGROUND Autologous fat grafting, while broadly indicated, is limited by unsatisfactory retention and often requires multiple procedures to achieve durable outcomes. Graft survival is strongly influenced by magnitude and duration of post-engraftment ischemia. Calcitriol is… read more here.
Keywords: xenograft model; retention; vitamin calcitriol; retention xenograft ... See more keywords
TMOD-09. A PATIENT-DERIVED XENOGRAFT MODEL MIMICKING RECURRENT PEDIATRIC MALIGNANT GLIOMA.
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/nox083.208
Abstract: Abstract BACKGROUND: Pediatric high grade glioma (pHGG) is a devastating cancer of the central nervous system. The prognosis of this most malignant form of brain tumor remains poor, largely due to the inherent resistance of… read more here.
Keywords: glioma; phgg; xenograft model; oncology ... See more keywords
Establishing a xenograft model with CD-1 nude mice to study human skin wound repair.
Sign Up to like & getrecommendations! Published in 2023 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000010465
Abstract: BACKGROUND A significant gap exists in the translatability of small animal models to human subjects. One important factor is poor laboratory models involving human tissue. Thus, we have created a viable postnatal human skin xenograft… read more here.
Keywords: human skin; xenograft model; skin; mice ... See more keywords
Establishment and Identification of Patient-Derived Xenograft Model for Oral Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/3135470
Abstract: Oral squamous cell carcinoma is the most common head and neck malignancy with high morbidity and mortality. Currently, platinum-based chemotherapy is the conventional chemotherapy regimen for patients with oral squamous cell carcinoma. However, due to… read more here.
Keywords: xenograft model; patient derived; oral squamous; derived xenograft ... See more keywords
Enhanced Intratumoral Delivery of SN38 as a Tocopherol Oxyacetate Prodrug Using Nanoparticles in a Neuroblastoma Xenograft Model
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-17-3811
Abstract: Purpose: Currently, read more here.
Keywords: sn38; cpt; tocopherol oxyacetate; xenograft model ... See more keywords
Abstract 3537: A novel orthotopic xenograft model of spontaneous metastasis for rhabdomyosarcoma using lingual intramuscular injection
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3537
Abstract: Rhabdomyosarcoma (RMS), a cancer characterized by the defective differentiation of skeletal muscle precursor cells, is the most common pediatric soft tissue sarcoma. Despite significant efforts to characterize the transcriptomic and genetic abnormalities of the disease,… read more here.
Keywords: injection; xenograft model; orthotopic; metastasis ... See more keywords
Establishment of a Zebrafish Xenograft Model for in Vivo Investigation of Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221116085
Abstract: Nasopharyngeal carcinoma (NPC) is a unique malignant tumor of the head and neck. Despite higher survival rates by the combination of radiotherapy and chemotherapy, the recurrence or metastasis of NPC still occurs at about 10%.… read more here.
Keywords: nasopharyngeal carcinoma; xenograft model; vivo; npc ... See more keywords