Articles with "xenograft mouse" as a keyword



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Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.

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Published in 2021 at "Acta pharmacologica Sinica"

DOI: 10.1038/s41401-021-00812-3

Abstract: Cln Three Requiring 9 (CTR9), a scaffold protein of the polymerase-associated factor-1 (PAF1) complex (PAF1c), is primarily localized in the nucleus of cells. Recent studies show that CTR9 plays essential roles in the development of… read more here.

Keywords: ctr9; xenograft mouse; hepatocellular carcinoma; transcriptional regulator ... See more keywords
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Identification for antitumor effects of tramadol in a xenograft mouse model using orthotopic breast cancer cells

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-01701-9

Abstract: In our previous research showed that tramadol having potential anti-tumor effect was associated with enhancement of oncological prognosis in patients with breast cancer surgery. As these effects have not been confirmed by clinical dose-regulated animal… read more here.

Keywords: tramadol; group; breast cancer; xenograft mouse ... See more keywords
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The Cytolethal Distending Toxin Subunit CdtB of Helicobacter hepaticus Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines

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Published in 2017 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2017.00268

Abstract: Cytolethal distending toxins (CDTs) are common among pathogenic bacteria of the human and animal microbiota. CDTs exert cytopathic effets, via their active CdtB subunit. No clear description of those cytopathic effects has been reported at… read more here.

Keywords: mouse models; cell lines; cdtb; cell ... See more keywords