The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts.
Sign Up to like & getrecommendations! Published in 2025 at "Cytoskeleton"
DOI: 10.1002/cm.22034
Abstract: A bipolar spindle composed of microtubules and many associated proteins functions to segregate chromosomes during cell division in all eukaryotes, yet both spindle size and architecture vary dramatically across different species and cell types. Targeting… read more here.
Keywords: egg extracts; tpx2 regulates; tpx2; xenopus egg ... See more keywords
Nuclear Pore Complex Assembly Using Xenopus Egg Extract.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2337-4_3
Abstract: Xenopus egg extract is a powerful tool for the in vitro investigation of complex cellular mechanisms. Here we describe how to obtain and employ interphase Xenopus egg extract to study nuclear pore complex assembly and… read more here.
Keywords: xenopus egg; nuclear pore; egg extract; pore complex ... See more keywords
Structural obstruction to full DNA replication in terminally differentiated skeletal muscle cells
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DOI: 10.1038/s44319-025-00554-x
Abstract: Terminal cell differentiation is often associated with permanent withdrawal from proliferation, termed the postmitotic state. Though widespread among vertebrates and determinant for their biology, the molecular underpinnings of this state are poorly understood. Postmitotic skeletal… read more here.
Keywords: replication; cell cycle; dna replication; xenopus egg ... See more keywords
Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2021.07.14.452321
Abstract: Microtubules are tubes of about 25 nm in diameter that are critically involved in a variety of cellular functions including motility, compartmentalization, and division. They are considered as pseudo-helical polymers whose constituent αβ-tubulin heterodimers share… read more here.
Keywords: porcine brain; egg cytoplasmic; microtubules assembled; xenopus egg ... See more keywords