ASPP2 enhances chemotherapeutic sensitivity through the down-regulation of XIAP expression in a p53 independent manner in hepatocellular carcinoma.
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DOI: 10.1016/j.bbrc.2018.11.181
Abstract: Apoptosis stimulated protein of p53-2 (ASPP2) induces the transcription of p53-targeted genes to stimulates its pro-apoptosis function. The poor chemotherapeutic sensitivity is associated with the decreased ASPP2 expression in many human cancers. Here, multiple genes… read more here.
Keywords: hepatocellular carcinoma; sensitivity; xiap expression; xiap ... See more keywords