Articles with "xii activation" as a keyword



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Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains

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Published in 2022 at "Blood Advances"

DOI: 10.1182/bloodadvances.2021005976

Abstract: Key Points The FXII EGF1 domain promotes surface binding, FXII activation on surfaces, and FXIIa activation of prekallikrein on surfaces. The FXII FN2 and KNG domains are part of a mechanism that restricts FXII activation… read more here.

Keywords: surface dependent; dependent factor; xii activation; model surface ... See more keywords