Anticancer compound XL765 as PI3K/mTOR dual inhibitor: A structural insight into the inhibitory mechanism using computational approaches
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DOI: 10.1371/journal.pone.0219180
Abstract: The PI3K-AKT-mTOR pathway is often a commonly disrupted pathway in human cancer and, therefore, it is widely exploited for cancer therapy. The inhibitors for the important proteins of the pathway including PI3K and mTOR have… read more here.
Keywords: pi3k mtor; mtor dual; xl765; compound ... See more keywords