Xian-Ling-Gu-Bao induced inflammatory stress rat liver injury: Inflammatory and oxidative stress playing important roles.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.111910
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Xian-Ling-Gu-Bao (XLGB) Fufang is an herbal formula that has been used in clinical settings to treat osteoporosis, osteoarthritis, aseptic bone necrosis, and climacteric syndrome. Despite its uses, XLGB treatment has been linked to… read more here.
Keywords: xlgb; xlgb lps; stress; liver injury ... See more keywords
Methodology improvement for network pharmacology to correct the deviation of deduced medicinal constituents and mechanism: Xian-Ling-Gu-Bao as an example.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115058
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Network pharmacology is extremely adaptive for investigating traditional ethnic drugs, especially the herbal medicines. However, challenges still hang over many related studies due to the limitations in the methodology of conventional network pharmacology.… read more here.
Keywords: xlgb; methodology; network pharmacology; pharmacology ... See more keywords
Xianling Gubao attenuates high glucose-induced bone metabolism disorder in MG63 osteoblast-like cells
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DOI: 10.1371/journal.pone.0276328
Abstract: Diabetes mellitus (DM) patients are prone to osteoporosis, and high glucose (HG) can affect bone metabolism. In the present study, we investigated the protective effects of traditional Chinese herbal formulation Xianling Gubao (XLGB) on HG-treated… read more here.
Keywords: apoptosis; related proteins; bone; high glucose ... See more keywords
Comparative Efficacy of Xianling Gubao Capsules in Improving Bone Mineral Density in Postmenopausal Osteoporosis: A Network Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.839885
Abstract: Objective The clinical efficacy of Xianling Gubao capsule (XLGB) and its combination therapy in the treatment of postmenopausal osteoporosis (PMOP) was systematically evaluated by frequency-based network meta-analysis. Methods We searched the China National Knowledge Infrastructure… read more here.
Keywords: meta analysis; efficacy xianling; analysis; network meta ... See more keywords