Luteolin-7-methylether from Leonurus japonicus inhibits estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19).
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DOI: 10.1016/j.ejphar.2020.173154
Abstract: Leonurus japonicus (motherwort) has been widely used to treat gynecological disorders, in which estrogen is often dysregulated, for a long time in China and other Asian countries. However, the chemical constituents and mechanisms underlying the… read more here.
Keywords: biosynthesis; estrogen biosynthesis; aromatase; xly29 ... See more keywords