Purine-Induced IFN-γ Promotes Uric Acid Production by Upregulating Xanthine Oxidoreductase Expression
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DOI: 10.3389/fimmu.2022.773001
Abstract: Objective Limiting purine intake, inhibiting xanthine oxidoreductase (XOR) and inhibiting urate reabsorption in proximal tubule by uricosuric drugs, to reduce serum uric acid (UA) levels, are recognized treatments for gout. However, the mechanism of increased… read more here.
Keywords: xanthine oxidoreductase; purine; expression; xor expression ... See more keywords