Renal cancer associated with Xp11.2 translocation/TFE3 gene fusion: Clinicopathological analysis of 13 cases.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2022.151908
Abstract: OBJECTIVE To explore the clinicopathological characteristics, immunohistochemical phenotype, diagnosis and differential diagnosis of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion. METHODS The clinical history, pathological morphology, immunohistochemical phenotype and related molecular test results… read more here.
Keywords: tfe3 gene; gene fusion; gene; translocation tfe3 ... See more keywords
Clinicopathologic Characteristics and Prognosis of Xp11.2 Translocation Renal Cell Carcinoma: Multicenter, Propensity Score Matching Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.04.015
Abstract: Micro‐Abstract We evaluated the clinicopathologic characteristics and prognosis of Xp11.2 translocation renal cell carcinoma (RCC) from a multicenter study. This rare neoplasm had more aggressive clinicopathologic features to involve lymph nodes at diagnosis. The age… read more here.
Keywords: xp11 translocation; prognosis; rcc; clear cell ... See more keywords
PD-L1 expression in Xp11.2 translocation renal cell carcinoma: Indicator of tumor aggressiveness
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DOI: 10.1038/s41598-017-02005-7
Abstract: Programmed death ligand-1 (PD-L1), a promising antitumor target, has proven clinical value against many malignancies. However, the PD-L1 content of Xp11.2 translocation renal cell carcinoma (Xp11.2 RCC) and its correlation with clinical outcomes remain unclear.… read more here.
Keywords: xp11 translocation; xp11 rcc; expression; translocation renal ... See more keywords
Metastatic adult Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion in complete remission
Sign Up to like & getrecommendations! Published in 2020 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2020.1847946
Abstract: Abstract Xp11 translocation renal cell carcinoma (RCC) accounts for most pediatric cases of RCC but is uncommon in adults. It has an aggressive course in adults with poor response to chemoradiation. We describe a 64-year-old… read more here.
Keywords: xp11 translocation; renal cell; complete remission; cell carcinoma ... See more keywords
Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2020-206681
Abstract: Aims Xp11 translocation renal cell carcinoma (RCC) is a distinctive subtype of RCC with TFE3 (Transcription Factor Binding to IGHM Enhancer 3) gene rearrangement. The gross features in most Xp11 translocation RCCs closely resemble clear… read more here.
Keywords: xp11 translocation; renal cell; six cases; translocation ... See more keywords
Abstract 3527: Clarification of the molecular mechanism for cancer development in Xp11.2 translocation renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-3527
Abstract: Xp11.2 translocation renal cell carcinoma (Xp11.2 tRCC) is a newly defined subset of RCC, which have chromosomal translocations involving the TFE3 transcription factor at Xp11.2. All translocations seen in Xp11.2 tRCC, including PRCC-TFE3, PSF-TFE3, ASPL-TFE3,… read more here.
Keywords: cancer; tfe3; cell; xp11 translocation ... See more keywords
Nephron-Sparing Surgery for Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical T1 Stage: A Multicenter Study in China
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DOI: 10.1245/s10434-020-08813-y
Abstract: Purpose To evaluate the oncologic efficacy and feasibility of nephron-sparing surgery (NSS) in adult Xp11.2 translocation renal cell carcinoma (RCC). Patients and Methods Seventy patients with Xp11.2 translocation RCC and 273 with conventional RCC from… read more here.
Keywords: xp11 translocation; adult xp11; nephron sparing; rcc ... See more keywords
ASO Author Reflections: The Oncologic Efficacy and Feasibility of Nephron-Sparing Surgery for Adult Xp11.2 Translocation Renal Cell Carcinoma
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DOI: 10.1245/s10434-020-08814-x
Abstract: Since the description of Xp11.2 translocation renal cell carcinoma as a clinicopathologic entity in 2001, it has attracted increasing attention. This study focused on the oncologic efficacy and feasibility of nephron-sparing surgery (NSS) in this… read more here.
Keywords: xp11 translocation; renal cell; carcinoma; translocation renal ... See more keywords
Gene Expression Analysis of Aggressive Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical Stage T1N0M0 to Identify Potential Prognostic and Therapeutic Biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020321
Abstract: Xp11.2 translocation renal cell carcinoma (tRCC), involving transcription factor E3 (TFE3) gene fusions, is a rare and aggressive RCC variant when present in adults and has been recently recognized as a unique entity in RCC.… read more here.
Keywords: cell; xp11; trcc; xp11 trcc ... See more keywords
Identification of Key Differentially Expressed mRNAs, miRNAs, lncRNAs, and circRNAs for Xp11 Translocation Renal Cell Carcinoma (RCC) Based on Whole-Transcriptome Sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14030723
Abstract: We carried out whole transcriptome sequencing (WTS) on the tumor and the matching adjacent normal tissues from five patients having Xp11 translocation renal cell carcinoma (RCC). This was performed in terms of obtaining more understanding… read more here.
Keywords: rcc; translocation rcc; xp11 translocation; differentially expressed ... See more keywords