Differential sensitivities of cellular XPA and PARP‐1 to arsenite inhibition and zinc rescue
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DOI: 10.1016/j.taap.2017.05.031
Abstract: &NA; Arsenite directly binds to the zinc finger domains of the DNA repair protein poly (ADP ribose) polymerase (PARP)‐1, and inhibits PARP‐1 activity in the base excision repair (BER) pathway. PARP inhibition by arsenite enhances… read more here.
Keywords: dna damage; xpa; zinc; xpa parp ... See more keywords