Performance of the Xpert MTB/RIF Ultra Assay for Determining Cause of Death by TB in Tissue Samples Obtained by Minimally Invasive Autopsies
Sign Up to like & getrecommendations! Published in 2020 at "Chest"
DOI: 10.1016/j.chest.2020.06.071
Abstract: An estimated 1.5 million deaths were attributable to TB in 2018. However, some uncertainty exists as to the exact global figures, given that approximately 30% of incident cases are not diagnosed, and because of the… read more here.
Keywords: death; performance xpert; cause death; mtb rif ... See more keywords
Performance of Xpert MTB/RIF Ultra assay on respiratory and extra-respiratory samples in a high-resource setting with a low tuberculosis prevalence.
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2020.115235
Abstract: The Xpert MTB/RIF assay is a molecular assay that has improved the detection of tuberculosis and rifampicin resistance. However, its sensitivity is limited in patients with paucibacillary disease. Xpert MTB/RIF Ultra has been developed to… read more here.
Keywords: tuberculosis; xpert; mtb rif; respiratory ... See more keywords
Analytical performance of the Xpert MTB/XDR® assay for tuberculosis and expanded resistance detection.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2021.115397
Abstract: In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The… read more here.
Keywords: xpert mtb; xdr assay; mtb xdr; resistance detection ... See more keywords
Comparative evaluation of Xpert MTB/RIF and the new Xpert MTB/RIF ultra with respiratory and extra-pulmonary specimens for tuberculosis case detection in a low incidence setting
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Tuberculosis and Other Mycobacterial Diseases"
DOI: 10.1016/j.jctube.2019.100094
Abstract: Background The Xpert MTB/RIF assay (Xpert) is an automated molecular test for the detection of tuberculosis and rifampin resistance (RIF-R), but it lacks sensitivity in smear-negative samples and some limitations in determination of RIF-R have… read more here.
Keywords: xpert mtb; tuberculosis; xpert; mtb rif ... See more keywords
Cost-Effectiveness Analysis of Xpert MTB/RIF for Multi-Outcomes of Presumptive Pulmonary Tuberculosis Patients in Thailand.
Sign Up to like & getrecommendations! Published in 2020 at "Value in health regional issues"
DOI: 10.1016/j.vhri.2019.09.010
Abstract: OBJECTIVES The cost-effectiveness of screening adult patients for pulmonary tuberculosis is not clear. As such, this study aims to identify the cost-effectiveness between the Xpert MTB/RIF assay and the sputum acid-fast bacilli (AFB) smear. Multi-outcomes… read more here.
Keywords: cost; xpert mtb; mtb rif; diagnosis ... See more keywords
Diagnostic values of Xpert MTB/RIF, T-SPOT.TB and adenosine deaminase for HIV-negative tuberculous pericarditis in a high burden setting: a prospective observational study
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73220-y
Abstract: The diagnosis of tuberculous pericarditis (TBP) remains challenging. This prospective study evaluated the diagnostic value of Xpert MTB/RIF (Xpert) and T-SPOT.TB and adenosine deaminase (ADA) for TBP in a high burden setting. A total of… read more here.
Keywords: spot; value; tuberculous pericarditis; spot adenosine ... See more keywords
Which sample type is better for Xpert MTB/RIF to diagnose adult and pediatric pulmonary tuberculosis?
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DOI: 10.1042/bsr20200308
Abstract: Abstract Objective: This review aimed to identify proper respiratory-related sample types for adult and pediatric pulmonary tuberculosis (PTB), respectively, by comparing performance of Xpert MTB/RIF when using bronchoalveolar lavage (BAL), induced sputum (IS), expectorated sputum… read more here.
Keywords: adult; xpert mtb; mtb rif; group ... See more keywords
Rifampicin Resistance and Multidrug-Resistant Tuberculosis Detection Using Xpert MTB/RIF in Wuhan, China: A Retrospective Study.
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DOI: 10.1089/mdr.2017.0114
Abstract: BACKGROUND The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA) can simultaneously detect the Mycobacterium tuberculosis (MTB) complex DNA and rifampicin (RFP) resistance and can rapidly determine RFP resistance and predict multidrug-resistant tuberculosis (MDR-TB). In this study,… read more here.
Keywords: rfp; mtb; resistance; mtb rif ... See more keywords
Xpert MTB/RIF Improves the Prognosis of Multidrug-Resistant Tuberculosis Patients Through Faster Diagnosis and Earlier Targeted Treatment: A Prospective Cohort Study.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial drug resistance"
DOI: 10.1089/mdr.2021.0149
Abstract: Objective: To evaluate the effectiveness of Xpert MTB/RIF in patients with multidrug-resistant tuberculosis (MDR-TB). Methods: Seventy-five patients with MDR-TB were enrolled in this prospective cohort study and were divided into two groups. The observation group… read more here.
Keywords: mtb rif; treatment; xpert mtb;
A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piaa159
Abstract: BACKGROUND Xpert MTB/RIF Ultra (Xpert Ultra) has improved the sensitivity to detect pulmonary tuberculosis (TB) in adults. However, there have been limited prospective evaluations of its diagnostic accuracy in children. METHODS We enrolled children undergoing… read more here.
Keywords: pulmonary tuberculosis; xpert ultra; xpert; mtb rif ... See more keywords
Impact of Xpert MTB/RIF in the Diagnosis of Childhood Tuberculosis in Rural Ethiopia.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of tropical pediatrics"
DOI: 10.1093/tropej/fmac055
Abstract: BACKGROUND This study assesses the impact of the Xpert MTB/RIF in the diagnosis of childhood tuberculosis (TB) in a rural hospital in a resource-constrained setting. METHODS Retrospective cross-sectional study in children evaluated for presumptive TB… read more here.
Keywords: diagnosis; mtb rif; childhood; xpert mtb ... See more keywords