XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia
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DOI: 10.3324/haematol.2018.210054
Abstract: β-thalassemia major (β-TM) is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of hemoglobin, leading to the accumulation of free a-globin chains that aggregate and cause ineffective erythropoiesis. We… read more here.
Keywords: xpo1 regulates; hsp70; globin chains; treatment ... See more keywords