Abstract 4049: The synergistic effect of melphalan and XPO1 inhibition in preclinical models of multiple myeloma
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DOI: 10.1158/1538-7445.am2017-4049
Abstract: Introduction: Significant increases in response/survival have been seen over the past several years; however, multiple myeloma (MM) remains incurable. In this study we have demonstrated that the XPO1 inhibitors (XPO1i), selinexor (SEL) and KPT-8602, sensitize… read more here.
Keywords: xpo1i mel; multiple myeloma; melphalan; preclinical models ... See more keywords