XPO1R749Q Mutations Co-occur with POLE Mutations in Cancer and can be Targeted to Overcome Chemoresistance.
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DOI: 10.1158/0008-5472.can-24-3112
Abstract: XPO1 is a nuclear export receptor that is essential for cell survival. Previous genomic analyses have identified recurrent XPO1 hotspot mutations in cancer. Here, we conducted a large-scale genomic analysis of 217,570 cancer patients to… read more here.
Keywords: cancer; xpo1r749q mutations; mutations cancer; pole mutations ... See more keywords