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XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity.

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0 Published in 2018 at "DNA repair"

DOI: 10.1016/j.dnarep.2018.02.004

Abstract: Aprataxin (APTX) is a DNA-adenylate hydrolase that removes 5'-AMP blocking groups from abortive ligation repair intermediates. XRCC1, a multi-domain protein without catalytic activity, interacts with a number of known repair proteins including APTX, modulating and… read more here.

Keywords: dna; xrcc1 phosphorylation; activity; xrcc1 ... See more keywords