Curcumin analog, GO-Y078, induces HO-1 transactivation-mediated apoptotic cell death of oral cancer cells by triggering MAPK pathways and AP-1 DNA-binding activity
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2061349
Abstract: ABSTRACT Background GO-Y078, a new synthetic analogue of curcumin (CUR), has higher oral bioavailability and anticancer activity than CUR, but the oncostatic effect of GO-Y078 on oral squamous cell carcinoma (OSCC) is largely unknown. Research… read more here.
Keywords: cell; binding activity; dna binding; y078 ... See more keywords
Curcumin analog, GO‐Y078, overcomes resistance to tumor angiogenesis inhibitors
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DOI: 10.1111/cas.13741
Abstract: Tumor angiogenesis inhibition is one of the most potent strategies in cancer chemotherapy. From past clinical studies, inhibition of the vascular endothelial growth factor pathway successfully treats malignant tumors. However, vascular endothelial growth factor inhibitors… read more here.
Keywords: angiogenesis; vascular endothelial; y078; inhibition ... See more keywords