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Abstract P6-03-06:ESR1mutant alleles induce differential sensitivity to combination endocrine and targeted therapies

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs19-p6-03-06

Abstract: Background: Estrogen receptor alpha (ESR1) mutations in estrogen receptor positive (ER+) metastatic breast cancer drive the development of acquired resistance to endocrine therapy. However, ESR1 mutation status does not currently guide treatment decisions due to… read more here.

Keywords: combination; treatment; esr1 mutant; sensitivity ... See more keywords