Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
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DOI: 10.1038/s42003-021-02286-9
Abstract: Mechanical forces control cell behavior, including cancer progression. Cells sense forces through actomyosin to activate YAP. However, the regulators of F-actin dynamics playing relevant roles during mechanostransduction in vitro and in vivo remain poorly characterized.… read more here.
Keywords: cholangiocarcinoma development; yap mechanotransduction; empowers yap; fascin1 empowers ... See more keywords
Enigma proteins regulate YAP mechanotransduction
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.221788
Abstract: ABSTRACT Human cells can sense mechanical stress acting upon integrin adhesions and respond by sending the YAP (also known as YAP1) and TAZ (also known as WWTR1) transcriptional co-activators to the nucleus to drive TEAD-dependent… read more here.
Keywords: regulate yap; enigma proteins; proteins regulate; mechanotransduction ... See more keywords