YAP nuclear‐cytoplasmic translocation is regulated by mechanical signaling, protein modification, and metabolism
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DOI: 10.1002/cbin.11345
Abstract: Nuclear‐cytoplasmic transport is necessary for the biological function of nuclear proteins. The mechanism underlying this process is very complex and has been a subject of intense research. Yes‐associated protein (YAP), a Hippo signaling pathway effector,… read more here.
Keywords: protein; signaling protein; nuclear cytoplasmic; protein modification ... See more keywords
A Glowing Opportunity to Target YAP in Lung Fibrosis
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DOI: 10.1165/rcmb.2022-0082ed
Abstract: Idiopathic pulmonary fibrosis (IPF) remains a devastating disease. Current therapies can slow progression but fail to fully address the medical need. The underlying cause of IPF is unknown, but a wide array of mechanisms driving… read more here.
Keywords: yap nuclear; nuclear localization; fibrosis; kinase ... See more keywords