Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.
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DOI: 10.1016/j.celrep.2020.107990
Abstract: The Hippo/Yes-associated protein (YAP) pathway has pivotal roles in innate immune responses against pathogens in macrophages. However, the role of YAP in macrophages during atherosclerosis and its mechanism of YAP activation remain unknown. Here, we… read more here.
Keywords: linked ubiquitination; yap promotes; macrophage k63; k63 linked ... See more keywords