Yap signalling regulates ductular reactions in mice with CRISPR/Cas9-induced glycogen storage disease type Ia
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DOI: 10.1080/19768354.2022.2139755
Abstract: ABSTRACT Glycogen storage disease type Ia (GSD-Ia) is caused by a deficiency in the glucose-6-phosphatase (G6Pase, G6pc) enzyme, which catalyses the final step of gluconeogenesis and glycogenolysis. Accumulation of G6pc can lead to an increase… read more here.
Keywords: crispr cas9; disease; g6pc mice; yap signalling ... See more keywords
Live imaging YAP signalling in mouse embryo development
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DOI: 10.1098/rsob.210335
Abstract: YAP protein is a critical regulator of mammalian embryonic development. By generating a near-infrared fusion YAP reporter mouse line, we have achieved high-resolution live imaging of YAP localization during mouse embryonic development. We have validated… read more here.
Keywords: live imaging; imaging yap; development; mouse ... See more keywords