WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth.
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DOI: 10.1158/0008-5472.can-22-3003
Abstract: Noncanonical Wnt signaling by WNT5a has oncogenic and tumor suppressive activities, but downstream pathways mediating these specific effects remain to be fully established. In a subset of prostate cancer organoid culture and xenograft models, inhibition… read more here.
Keywords: hippo pathway; ror2; yap1 activity; tumor ... See more keywords