MZF1 and GABP Cooperate with Sox2 in Regulating the Expression of YAP1 in Cancer Cells
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells"
DOI: 10.1002/stem.2705
Abstract: The transcription factor YAP1 is a major effector of the tumor suppressive Hippo signaling pathway and is also necessary to maintain pluripotency in embryonic stem cells. Elevated levels of YAP1 expression antagonize the tumor suppressive… read more here.
Keywords: yap1; yap1 expression; expression; sox2 ... See more keywords
The role of YAP1 in survival prediction, immune modulation, and drug response: A pan-cancer perspective
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1012173
Abstract: Introduction Dysregulation of the Hippo signaling pathway has been implicated in multiple pathologies, including cancer, and YAP1 is the major effector of the pathway. In this study, we assessed the role of YAP1 in prognostic… read more here.
Keywords: pan cancer; yap1 expression; cancer; expression ... See more keywords
The Impact of Yes-Associated Protein 1 (YAP1) Expression Patterns in Locally Advanced Breast Cancer: Associations with Pathological Response and Tumor Features
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DOI: 10.3390/medicina61071297
Abstract: Background and Objectives: The Hippo pathway, via Yes-associated protein 1 (YAP1), regulates cell proliferation, apoptosis, and tissue regeneration. Aberrant YAP1 activation is linked to tumor progression and immune evasion in various cancers, including breast carcinoma,… read more here.
Keywords: treatment; breast; yap1 expression; tumor ... See more keywords