Abstract 973: The mitochondrial deoxyguanosine kinase regulates lung adenocarcinoma cancer stem-like cells through AMPK/YAP1 signaling
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-973
Abstract: Metastasis involves the dissemination of tumor cells from primary site to distant organs, and the colonization of disseminated cancer cells to establish distant metastases. Some of the disseminated cancer stem-like cells (CSC) are able to… read more here.
Keywords: dgk; cancer; yap1 signaling; tumor ... See more keywords
Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling
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DOI: 10.3390/ijms232314516
Abstract: Sphingosine kinase 1 (SPHK1) and the sphingosine-1-phosphate (S1P) signaling pathway have been shown to play a role in pulmonary arterial hypertension (PAH). S1P is an important stimulus for pulmonary artery smooth muscle cell (PASMC) proliferation… read more here.
Keywords: hypertension; muscle; yap1 signaling; mediated pulmonary ... See more keywords