VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23307
Abstract: Epidermal squamous cell carcinoma (SCC) develops in response to ultraviolet light exposure and is among the most common cancers. The transglutaminase 2 cancer cell survival protein stimulates the activity of the YAP1/TEAD transcription complex to… read more here.
Keywords: yap1 tead; cancer phenotype; expression; cancer ... See more keywords
NOTCH-YAP1/TEAD-DNMT1 axis drives hepatocyte reprogramming into intrahepatic cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.05.007
Abstract: BACKGROUND AND AIM Intrahepatic cholangiocarcinoma (ICC) is a devastating liver cancer with extremely high intra- and inter-tumoral molecular heterogeneity, partly due to its diverse cellular origins. We investigated clinical relevance and the molecular mechanisms underlying… read more here.
Keywords: yap1 tead; dnmt1; yap1; icc development ... See more keywords