The exponential growth of autophagy‐related research: from the humble yeast to the Nobel Prize
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12594
Abstract: Autophagy was discovered more than half a century ago. In the early days, autophagy was studied mostly through the use of biochemical methods and electron microscopy. In the 1990s, yeast genetics was introduced to this… read more here.
Keywords: research; growth autophagy; yeast; nobel prize ... See more keywords
Diacylglycerol kinase alleviates autophagic degradation of the endoplasmic reticulum in SPT10‐deficient yeast to enhance triterpene biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14418
Abstract: A recent study showed that deletion of the gene encoding the transcription regulator SuPpressor of Ty10 (SPT10) increases total phospholipids, and our previous study established a critical link between phospholipids and the mevalonate/ergosterol (MEV/ERG) pathway,… read more here.
Keywords: endoplasmic reticulum; triterpene; spt10; spt10 yeast ... See more keywords
Hsp90 and J-protein family chaperones are not directly involved in cellular iron-sulfur protein assembly and iron regulation in yeast.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14612
Abstract: Systematic studies have revealed interactions between components of the Hsp90 chaperone system and Fe/S protein biogenesis or iron regulation. In addition, two chloroplast-localized DnaJ-like proteins, DJA5 and DJA6, function as specific iron donors in plastidial… read more here.
Keywords: iron; yeast; cellular iron; iron regulation ... See more keywords
Bio‐Engineering Yeast Cells Biolenses by Reshaping Intracellular Vacuoles
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Optical Materials"
DOI: 10.1002/adom.202400164
Abstract: An intriguing field of research has recently emerged in which biological cells can be demonstrated to behave as photonics devices, such as optical microlenses. This research highlights yeast cells as promising candidates for engineering biolenses… read more here.
Keywords: cells biolenses; yeast; engineering yeast; yeast cells ... See more keywords
Following nature's roadmap: folding factors from plasma cells led to improvements in antibody secretion in S. cerevisiae.
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology journal"
DOI: 10.1002/biot.201600631
Abstract: Therapeutic protein production in yeast is a reality in industry with an untapped potential to expand to more complex proteins, such as full-length antibodies. Despite numerous engineering approaches, cellular limitations are preventing the use of… read more here.
Keywords: antibody; antibody secretion; plasma cells; yeast ... See more keywords
Development of a temperature‐responsive yeast cell factory using engineered Gal4 as a protein switch
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26544
Abstract: Conflict between cell growth and product accumulation is frequently encountered in biosynthesis of secondary metabolites. Herein, a temperature‐dependent dynamic control strategy was developed by modifying the GAL regulation system to facilitate two‐stage fermentation in yeast.… read more here.
Keywords: gal4; temperature; temperature responsive; yeast ... See more keywords
Enhanced direct ethanol production by cofactor optimization of cell surface‐displayed xylose isomerase in yeast
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Progress"
DOI: 10.1002/btpr.2478
Abstract: Xylose isomerase (XylC) from Clostridium cellulovorans can simultaneously perform isomerization and fermentation of d‐xylose, the main component of lignocellulosic biomass, and is an attractive candidate enzyme. In this study, we optimized a specified metal cation… read more here.
Keywords: system; xylose isomerase; xylc; yeast ... See more keywords
An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2017 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22093
Abstract: P450 activity is required to metabolically activate many chemical carcinogens, rendering them highly genotoxic. CYP3A4 is the most abundantly expressed P450 enzyme in the liver, accounting for most drug metabolism and constituting 50% of all… read more here.
Keywords: saccharomyces cerevisiae; genotoxicity; human cyp3a4; yeast ... See more keywords
Efficient biohydrogen and bioelectricity production from xylose by microbial fuel cell with newly isolated yeast of Cystobasidium slooffiae
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Energy Research"
DOI: 10.1002/er.4922
Abstract: Although xylose is the secondary dominant sugar derived from biomass, the conversion of xylose to energy products is quite challenging. In this work, a new exoelectrogenic yeast strain (Cystobasidium slooffiae strain JSUX1) that can generate… read more here.
Keywords: yeast; fuel cell; cystobasidium slooffiae; microbial fuel ... See more keywords
Pretreatment With a Selected Strain of Baker's Yeast, GY007, Prevents the Accumulation of Galactose Metabolites Following Dietary Galactose Exposure in a GALT‐Null Rat Model of Classic Galactosemia
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.70116
Abstract: The current standard of care for patients with classic galactosemia (CG) involves lifelong dietary restriction of high galactose foods, including most dairy products. Here, we present the results of a pilot study testing whether pretreatment… read more here.
Keywords: galactose exposure; yeast; gy007; dietary galactose ... See more keywords
Context‐Dependent Food Preferences and Comparative Decision‐Making in Slime Mold Physarella oblonga
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.70023
Abstract: Slime molds, despite their unicellular nature, exhibit complex behaviors and problem‐solving abilities that have fascinated researchers. They are widely utilized as model organisms in behavioral studies. In this study, we examined the feeding preferences of… read more here.
Keywords: mold physarella; slime mold; yeast; physarella oblonga ... See more keywords