The exponential growth of autophagy‐related research: from the humble yeast to the Nobel Prize
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12594
Abstract: Autophagy was discovered more than half a century ago. In the early days, autophagy was studied mostly through the use of biochemical methods and electron microscopy. In the 1990s, yeast genetics was introduced to this… read more here.
Keywords: research; growth autophagy; yeast; nobel prize ... See more keywords
Diacylglycerol kinase alleviates autophagic degradation of the endoplasmic reticulum in SPT10‐deficient yeast to enhance triterpene biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14418
Abstract: A recent study showed that deletion of the gene encoding the transcription regulator SuPpressor of Ty10 (SPT10) increases total phospholipids, and our previous study established a critical link between phospholipids and the mevalonate/ergosterol (MEV/ERG) pathway,… read more here.
Keywords: endoplasmic reticulum; triterpene; spt10; spt10 yeast ... See more keywords
Hsp90 and J-protein family chaperones are not directly involved in cellular iron-sulfur protein assembly and iron regulation in yeast.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14612
Abstract: Systematic studies have revealed interactions between components of the Hsp90 chaperone system and Fe/S protein biogenesis or iron regulation. In addition, two chloroplast-localized DnaJ-like proteins, DJA5 and DJA6, function as specific iron donors in plastidial… read more here.
Keywords: iron; yeast; cellular iron; iron regulation ... See more keywords
Following nature's roadmap: folding factors from plasma cells led to improvements in antibody secretion in S. cerevisiae.
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology journal"
DOI: 10.1002/biot.201600631
Abstract: Therapeutic protein production in yeast is a reality in industry with an untapped potential to expand to more complex proteins, such as full-length antibodies. Despite numerous engineering approaches, cellular limitations are preventing the use of… read more here.
Keywords: antibody; antibody secretion; plasma cells; yeast ... See more keywords
Development of a temperature‐responsive yeast cell factory using engineered Gal4 as a protein switch
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26544
Abstract: Conflict between cell growth and product accumulation is frequently encountered in biosynthesis of secondary metabolites. Herein, a temperature‐dependent dynamic control strategy was developed by modifying the GAL regulation system to facilitate two‐stage fermentation in yeast.… read more here.
Keywords: gal4; temperature; temperature responsive; yeast ... See more keywords
Enhanced direct ethanol production by cofactor optimization of cell surface‐displayed xylose isomerase in yeast
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Progress"
DOI: 10.1002/btpr.2478
Abstract: Xylose isomerase (XylC) from Clostridium cellulovorans can simultaneously perform isomerization and fermentation of d‐xylose, the main component of lignocellulosic biomass, and is an attractive candidate enzyme. In this study, we optimized a specified metal cation… read more here.
Keywords: system; xylose isomerase; xylc; yeast ... See more keywords
An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2017 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22093
Abstract: P450 activity is required to metabolically activate many chemical carcinogens, rendering them highly genotoxic. CYP3A4 is the most abundantly expressed P450 enzyme in the liver, accounting for most drug metabolism and constituting 50% of all… read more here.
Keywords: saccharomyces cerevisiae; genotoxicity; human cyp3a4; yeast ... See more keywords
Efficient biohydrogen and bioelectricity production from xylose by microbial fuel cell with newly isolated yeast of Cystobasidium slooffiae
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Energy Research"
DOI: 10.1002/er.4922
Abstract: Although xylose is the secondary dominant sugar derived from biomass, the conversion of xylose to energy products is quite challenging. In this work, a new exoelectrogenic yeast strain (Cystobasidium slooffiae strain JSUX1) that can generate… read more here.
Keywords: yeast; fuel cell; cystobasidium slooffiae; microbial fuel ... See more keywords
Effect of glucose levels on carbon flow rate, antioxidant status, and enzyme activity of yeast during fermentation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11887
Abstract: BACKGROUND The physiological metabolism of yeast has a significant impact on the quality of fermentation products, this research was to clarify the yeast metabolism in response to a changing glucose content environment, especially in fermentation… read more here.
Keywords: yeast; flow rate; cell; activity ... See more keywords
Behavioral manipulation of Drosophila suzukii for pest control: high attraction to yeast enhances insecticide efficacy when applied on leaves.
Sign Up to like & getrecommendations! Published in 2021 at "Pest management science"
DOI: 10.1002/ps.6699
Abstract: BACKGROUND The invasive pest, Drosophila suzukii attacks fresh soft-skinned fruit. Broad-spectrum insecticides are implemented for control but there is need to reduce environmental risks and insecticide residues on fruits. Hanseniaspora uvarum is a yeast frequently… read more here.
Keywords: drosophila suzukii; attraction yeast; efficacy; yeast ... See more keywords
An efficient method for isolating mating‐competent cells from bottom‐fermenting yeast using mating pheromone‐supersensitive mutants
Sign Up to like & getrecommendations! Published in 2018 at "Yeast"
DOI: 10.1002/yea.3291
Abstract: Crossbreeding is an effective approach to construct novel yeast strains with preferred characteristics; however, it is difficult to crossbreed strains of brewer's yeast, especially the bottom‐fermenting yeast Saccharomyces pastorianus, because of the relative inefficiency of… read more here.
Keywords: fermenting yeast; yeast strains; yeast; mating pheromone ... See more keywords