A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity
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DOI: 10.3390/genes10100770
Abstract: Knowledge about synthetic lethality can be applied to enhance the efficacy of anticancer therapies in individual patients harboring genetic alterations in their cancer that specifically render it vulnerable. We investigated the potential for high-resolution phenomic… read more here.
Keywords: ontology; yeast phenomic; gene; deoxycytidine kinase ... See more keywords