Differential Interactions of Molecular Chaperones and Yeast Prions
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DOI: 10.3390/jof8020122
Abstract: Baker’s yeast Saccharomyces cerevisiae is an important model organism that is applied to study various aspects of eukaryotic cell biology. Prions in yeast are self-perpetuating heritable protein aggregates that can be leveraged to study the… read more here.
Keywords: yeast prions; molecular chaperones; propagation; differential interactions ... See more keywords
Hsp40/JDP Requirements for the Propagation of Synthetic Yeast Prions
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DOI: 10.3390/v14102160
Abstract: Yeast prions are protein-based transmissible elements, most of which are amyloids. The chaperone protein network in yeast is inexorably linked to the spreading of prions during cell division by fragmentation of amyloid prion aggregates. Specifically,… read more here.
Keywords: jdp; prion; propagation synthetic; yeast prions ... See more keywords
The Mutability of Yeast Prions
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DOI: 10.3390/v14112337
Abstract: Prions replicate by a self-templating mechanism. Infidelity in the process can lead to the emergence of new infectious structures, referred to as variants or strains. The question of whether prions are prone to mis-templating is… read more here.
Keywords: transmutable variants; yeast prions; faithful propagating; mutability yeast ... See more keywords