An Intradermal Model for Yersinia pestis Inoculation.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9541-7_1
Abstract: The dermis and the subcutaneous space vary in many fundamental characteristics, which include composition of lymphatic vessels, density of blood vasculature, and cells of the immune response. Traditional approaches employ the subcutaneous space as the… read more here.
Keywords: yersinia pestis; intradermal model; model; inoculation ... See more keywords
Real-Time Monitoring of Yersinia pestis Promoter Activity by Bioluminescence Imaging.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9541-7_7
Abstract: Bioluminescence imaging (BLI) has become a major strategy for real-time analysis of dynamic biological processes. In particular, bioluminescent reporter microorganisms have been designed to advance our understanding of infectious diseases. Non-invasive monitoring of light-emitting pathogenic… read more here.
Keywords: time monitoring; real time; bioluminescence imaging; time ... See more keywords
Investigation of Yersinia pestis and Yersinia pseudotuberculosis strains from Georgia and neighboring countries in the Caucasus by high-density SNP microarray
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Microbiology"
DOI: 10.1007/s00203-018-1545-8
Abstract: Yersinia pestis, the causative agent of plague, is a recently evolved clone of the enteropathogenic bacterium Yersinia pseudotuberculosis. Y. pestis has been extensively studied for decades; however, there are insufficient data about the intra-species diversity… read more here.
Keywords: microarray; pestis; yersinia; yersinia pestis ... See more keywords
Optimization and One-Step Purification of Recombinant V Antigen Production from Yersinia pestis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biotechnology"
DOI: 10.1007/s12033-019-00234-x
Abstract: The purpose of this study was to develop an efficient and inexpensive method for the useful production of recombinant protein V antigen, an important virulence factor for Yersinia pestis. To this end, the synthetic gene… read more here.
Keywords: step purification; production; recombinant; antigen ... See more keywords
Molecular detection of Rickettsia spp., Borrelia spp., Bartonella spp. and Yersinia pestis in ectoparasites of endemic and domestic animals in southwest Madagascar.
Sign Up to like & getrecommendations! Published in 2020 at "Acta Tropica"
DOI: 10.1016/j.actatropica.2020.105339
Abstract: Little is known about the presence of vector-borne bacteria in southwest Madagascar. Anthropogenic alteration of natural habitats represents an important driver for the emergence of new diseases. Especially the involvement of livestock and the involuntary… read more here.
Keywords: spp; yersinia pestis; southwest madagascar; madagascar ... See more keywords
Plasmid-mediated doxycycline resistance in a Yersinia pestis strain isolated from a rat.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2017.09.015
Abstract: The emergence of antibiotic-resistant Yersinia pestis strains represents a public health concern. Two antibiotic-resistant Y. pestis strains isolated from Madagascar have been previously identified and characterised. Both strains carried conjugative plasmids that conferred resistance to… read more here.
Keywords: pestis strain; pestis strains; pestis; resistance ... See more keywords
A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.101
Abstract: Vaccination can significantly reduce worldwide morbidity and mortality to infectious diseases, thereby reducing the health burden as a result of microbial infections. Effective vaccines contain three components: a delivery system, an antigenic component of the… read more here.
Keywords: challenge; model; becc438; yersinia pestis ... See more keywords
A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41923
Abstract: Massively parallel sequencing technology coupled with saturation mutagenesis has provided new and global insights into gene functions and roles. At a simplistic level, the frequency of mutations within genes can indicate the degree of essentiality.… read more here.
Keywords: positional significance; yersinia pestis; significance; gene ... See more keywords
Integrative approach using Yersinia pestis genomes to revisit the historical landscape of plague during the Medieval Period
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1812865115
Abstract: Significance While our knowledge of modern plague reservoirs and their hosts is extensive, we have little to no knowledge about the origin of the Medieval plague pandemics or the routes of transmission involved in their… read more here.
Keywords: medieval period; plague; pestis; yersinia pestis ... See more keywords
Reevaluation of the Role of Blocked Oropsylla hirsuta Prairie Dog Fleas (Siphonaptera: Ceratophyllidae) in Yersinia pestis (Enterobacterales: Enterobacteriaceae) Transmission
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Entomology"
DOI: 10.1093/jme/tjac021
Abstract: Abstract Prairie dogs in the western United States experience periodic epizootics of plague, caused by the flea-borne bacterial pathogen Yersinia pestis. An early study indicated that Oropsylla hirsuta (Baker), often the most abundant prairie dog… read more here.
Keywords: flea; transmission; prairie dog; oropsylla hirsuta ... See more keywords
Challenging Ancient DNA Results About Putative HLA Protection or Susceptibility to Yersinia pestis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac073
Abstract: Abstract In a recent article, Immel et al. (Immel A, Key FM, Szolek A, Barquera R, Robinson MK, Harrison GF, Palmer WH, Spyrou MA, Susat J, Krause-Kyora B, et al. 2021. Analysis of genomic DNA… read more here.
Keywords: protection susceptibility; hla protection; dna; yersinia pestis ... See more keywords