Investigation of Yersinia pestis and Yersinia pseudotuberculosis strains from Georgia and neighboring countries in the Caucasus by high-density SNP microarray
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Microbiology"
DOI: 10.1007/s00203-018-1545-8
Abstract: Yersinia pestis, the causative agent of plague, is a recently evolved clone of the enteropathogenic bacterium Yersinia pseudotuberculosis. Y. pestis has been extensively studied for decades; however, there are insufficient data about the intra-species diversity… read more here.
Keywords: microarray; pestis; yersinia; yersinia pestis ... See more keywords
Influence of Specific Bacteriophage on the Level of Vesicle Formation and Morphology of Cells of Yersinia pseudotuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4180-0
Abstract: Incubation of Yersinia pseudotuberculosis cells grown on a solid medium with pseudotuberculous diagnostic bacteriophage for 20 min at 37oC led to a significant decrease in the concentration of both components of the system. This effect… read more here.
Keywords: bacteriophage; yersinia pseudotuberculosis; vesicle formation;
Non-Specific Porins of Yersinia pseudotuberculosis as Inductors of Experimental Hyperthyroidism in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04433-z
Abstract: In vivo experiments showed that antibodies to OmpC and OmpF porins of Yersinia pseudotuberculosis increased thyroxine (T4) level in the blood of experimental animals. The mice were immunized with different antigens: recombinant OmpF porin in… read more here.
Keywords: ompf porin; non specific; porins yersinia; recombinant ompf ... See more keywords
ZntR positively regulates T6SS4 expression in Yersinia pseudotuberculosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Microbiology"
DOI: 10.1007/s12275-017-6540-2
Abstract: The type VI secretion system (T6SS) is a widespread and versatile protein secretion system found in most Gram-negative bacteria. Studies of T6SS have mainly focused on its role in virulence toward host cells and inter-bacterial… read more here.
Keywords: zinc; regulates t6ss4; zntr; expression ... See more keywords
Oral vaccination against plague using Yersinia pseudotuberculosis.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2016.03.030
Abstract: Yersinia pestis, the agent of plague, is among the deadliest bacterial pathogens affecting humans, and is a potential biological weapon. Because antibiotic resistant strains of Yersinia pestis have been observed or could be engineered for… read more here.
Keywords: plague; pestis; vaccine; vaccination ... See more keywords
Systemic Yersinia pseudotuberculosis as a Cause of Osteomyelitis in a Captive Ring-tailed Lemur (Lemur catta).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2018.08.004
Abstract: Yersinia pseudotuberculosis and Yersinia enterocolitica are ubiquitous pathogens with wildlife and domestic animal reservoirs. Outbreaks of 'non-plague' yersiniosis in man and non-human primates are reported frequently (including zoological specimens and research breeding colonies) and are usually… read more here.
Keywords: lemur; pseudotuberculosis; yersinia pseudotuberculosis; osteomyelitis ... See more keywords
The stringent response factor, RelA, positively regulates T6SS4 expression through the RovM/RovA pathway in Yersinia pseudotuberculosis.
Sign Up to like & getrecommendations! Published in 2019 at "Microbiological research"
DOI: 10.1016/j.micres.2018.12.002
Abstract: The type VI secretion system (T6SS) is a versatile molecular machinery widely distributed in Gram-negative bacteria. The activity of the T6SS is tightly regulated by various mechanisms, including quorum sensing (QS), iron concentration, and transcriptional… read more here.
Keywords: response; stringent response; rela positively; expression ... See more keywords
Humoral and cellular immune correlates of protection against bubonic plague by a live Yersinia pseudotuberculosis vaccine.
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DOI: 10.1016/j.vaccine.2018.11.022
Abstract: Immunization with the live-attenuated Yersinia pseudotuberculosis VTnF1 strain producing a Yersinia pestis F1 pseudocapsule efficiently protects mice against bubonic and pneumonic plague. In clinical trials, demonstration of a plague vaccine's efficacy in humans will not… read more here.
Keywords: protection; correlates protection; plague; humoral cellular ... See more keywords
Remodeling Yersinia pseudotuberculosis to generate a highly immunogenic outer membrane vesicle vaccine against pneumonic plague
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2109667119
Abstract: Significance Yersinia pestis, the etiologic agent of plague, has been responsible for high mortality in several epidemics throughout human history. This plague bacillus has been used as a biological weapon during human history and is… read more here.
Keywords: outer membrane; remodeling yersinia; plague; yersinia pseudotuberculosis ... See more keywords
The Yersinia pseudotuberculosis Cpx envelope stress system contributes to transcriptional activation of rovM
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DOI: 10.1080/21505594.2018.1556151
Abstract: ABSTRACT The Gram-negative enteropathogen Yersinia pseudotuberculosis possesses a number of regulatory systems that detect cell envelope damage caused by noxious extracytoplasmic stresses. The CpxA sensor kinase and CpxR response regulator two-component regulatory system is one… read more here.
Keywords: rova expression; rovm; expression; cpxr ... See more keywords
Genomic insights into a sustained national outbreak of Yersinia pseudotuberculosis.
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DOI: 10.1093/gbe/evw285
Abstract: In 2014, a sustained outbreak of yersiniosis due to Yersinia pseudotuberculosis occurred across all major cities in New Zealand (NZ), with a total of 220 laboratory-confirmed cases, representing one of the largest ever reported outbreaks… read more here.
Keywords: national outbreak; genomic insights; sustained national; insights sustained ... See more keywords