Articles with "yl001" as a keyword



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Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.17207

Abstract: Eg5 is a kinesin spindle protein that controls chromosomal segregation in mitosis and is thus a critical drug target for cancer therapy. We report the discovery of a potent, selective inhibitor of Eg5 designated YL001.… read more here.

Keywords: cancer; inhibits tumor; yl001; eg5 inhibitor ... See more keywords