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Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1392
Abstract: YL143 was identified as a novel wild‐type sparing EGFRT790M inhibitor with good pharmacokinetic properties. It potently suppresses EGFRL858R/T790M with an 50% inhibitory concentration (IC50) value of 2.0 ± 0.3 nmol/L, but is approximately 92‐folds less…
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Keywords:
yl143;
inhibitor;
novel mutant;
egfrl858r t790m ... See more keywords