Catalytic enantioselective intramolecular 1,3-dipolar cycloaddition of azomethine ylides with fluorinated dipolarophiles.
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DOI: 10.1039/d2cc02902b
Abstract: An enantioselective synthesis of polycyclic fluorinated pyrrolidines has been achieved by Cu-catalyzed intramolecular 1,3-dipolar cycloaddition of azomethine ylides with fluorinated dipolarophiles. The method displays a wide scope and afforded the desired cycloadducts in high yields… read more here.
Keywords: dipolar cycloaddition; intramolecular dipolar; cycloaddition azomethine; ylides fluorinated ... See more keywords