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   Articles with "ym1" as a keyword



Irreversible evolutionary loss of chitin‐degrading ability in the chitinase‐like protein Ym1 under positive selection in rodents

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recommendations! Published in 2023 at "Protein Science"

DOI: 10.1002/pro.4620

Abstract: Ym1 (chitinase‐like 3, Chil3) expressed in mice is a nonenzymatic chitinase‐like protein, which shows 67% identity with mouse acidic chitinase (Chia). Similar to Chia, Ym1 is overexpressed in asthma and parasitic infections in mouse lungs.… read more here.

Keywords: ym1; chitinase like; chitinase; loss ... See more keywords

Characterization of a novel group I F-specific RNA bacteriophage isolated from human stool.

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recommendations! Published in 2021 at "Archives of microbiology"

DOI: 10.1007/s00203-021-02402-7

Abstract: A novel F-specific RNA bacteriophage (FRNAPH) YM1, affiliating to genogroup I (GI) of Levivirus, is isolated for the first time from human stool samples using double-layer agar plates with the Escherichia coli ATCC700891 as the… read more here.

Keywords: specific rna; novel; human stool; rna bacteriophage ... See more keywords

A wheat CC-NBS-LRR protein Ym1 confers WYMV resistance by recognizing viral coat protein

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-58816-0

Abstract: Ym1 is the most widely utilized gene for wheat yellow mosaic virus (WYMV) disease control in worldwide wheat breeding. Here, we successfully isolated the responsible gene for Ym1. It encodes a typical CC-NBS-LRR type R… read more here.

Keywords: ym1; protein; nbs lrr; coat protein ... See more keywords

Macrophagic Ym1 orchestrates γδT cell-derived IL-17 production and keratinocyte functionality to mediate psoriasis-like skin inflammation

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recommendations! Published in 2025 at "Communications Biology"

DOI: 10.1038/s42003-025-08628-1

Abstract: Psoriasis is a chronic inflammatory skin disease, with the IL-17 pathway being a key contributor. Ym1, a positionally cloned inflammation regulatory gene linked to various disorders, has an unclear effect on skin inflammation. In this… read more here.

Keywords: psoriasis like; ym1; skin inflammation; inflammation ... See more keywords

An update on Ym1 and its immunoregulatory role in diseases

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.891220

Abstract: Ym1 is a rodent-specific chitinase-like protein (CLP) lacking catalytic activity, whose cellular origins are mainly macrophages, neutrophils and other cells. Although the detailed function of Ym1 remains poorly understood, Ym1 has been generally recognized as… read more here.

Keywords: ym1; immunoregulatory role; ym1 immunoregulatory; role diseases ... See more keywords