Irreversible evolutionary loss of chitin‐degrading ability in the chitinase‐like protein Ym1 under positive selection in rodents
Sign Up to like & getrecommendations! Published in 2023 at "Protein Science"
DOI: 10.1002/pro.4620
Abstract: Ym1 (chitinase‐like 3, Chil3) expressed in mice is a nonenzymatic chitinase‐like protein, which shows 67% identity with mouse acidic chitinase (Chia). Similar to Chia, Ym1 is overexpressed in asthma and parasitic infections in mouse lungs.… read more here.
Keywords: ym1; chitinase like; chitinase; loss ... See more keywords
Characterization of a novel group I F-specific RNA bacteriophage isolated from human stool.
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DOI: 10.1007/s00203-021-02402-7
Abstract: A novel F-specific RNA bacteriophage (FRNAPH) YM1, affiliating to genogroup I (GI) of Levivirus, is isolated for the first time from human stool samples using double-layer agar plates with the Escherichia coli ATCC700891 as the… read more here.
Keywords: specific rna; novel; human stool; rna bacteriophage ... See more keywords
An update on Ym1 and its immunoregulatory role in diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.891220
Abstract: Ym1 is a rodent-specific chitinase-like protein (CLP) lacking catalytic activity, whose cellular origins are mainly macrophages, neutrophils and other cells. Although the detailed function of Ym1 remains poorly understood, Ym1 has been generally recognized as… read more here.
Keywords: ym1; immunoregulatory role; ym1 immunoregulatory; role diseases ... See more keywords