Functional crosstalk between the TIM22 complex and YME1 machinery maintains mitochondrial proteostasis and integrity.
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DOI: 10.1242/jcs.260060
Abstract: The TIM22 pathway cargos are essential for sustaining mitochondrial homeostasis as an excess of these proteins leads to proteostatic stress and cell death. Yme1 is an inner membrane metalloprotease that regulates protein quality control with… read more here.
Keywords: tim22 complex; tim22; yme1; complex yme1 ... See more keywords