Synthesis and Cytotoxicity of Selenium-Containing Dienones
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DOI: 10.1134/s1070363220020085
Abstract: Abstract The nucleophilic addition of benzoselenol occurs regioselectively at the β-carbon of the triple bond of 1,5-disubstituted pent-2-ene-4-yne-1-ones, pent-4-ene-2-yne-1-ones and pent-1-ene-4-yne-3-ones. The resulting selenium-containing conjugated dienones exhibit pronounced cytotoxicity against some tumor cell lines. read more here.
Keywords: cytotoxicity; selenium containing; ene yne; pent ene ... See more keywords