Piezo1 activation stimulates Na, K-ATPase-mediated ion transport in mouse lens
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731454
Abstract: Purpose: Lens ion homeostasis is dependent on Na, K-ATPase and NKCC1. TRPV4 and TRPV1 channels, which are mechanosensitive, are known to regulate the activity of both these transporters. Here, we examined another mechanosensitive channel, piezo1,… read more here.
Keywords: calcium; physiology; transport; atpase ... See more keywords
Tubeimoside I Antagonizes Yoda1-Evoked Piezo1 Channel Activation
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DOI: 10.3389/fphar.2020.00768
Abstract: Piezo1, a mechanosensitive Ca2+-permeable non-selective cationic ion channel protein, is involved in a wide range of biological processes and plays crucial roles in vascular development. However, the pharmacology of this protein is in its infancy.… read more here.
Keywords: piezo1; piezo1 channel; yoda1; pharmacology ... See more keywords
Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression
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DOI: 10.3390/ijms24097868
Abstract: Osteoarthritis (OA) is the most common degenerative joint disease causing pain and functional limitations. Physical activity as a clinically relevant, effective intervention alleviates pain and promotes joint function. In chondrocytes, perception and transmission of mechanical… read more here.
Keywords: expression; mechanosensitive ion; yoda1; piezo1 trpv4 ... See more keywords