Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer
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DOI: 10.1001/jamanetworkopen.2019.13968
Abstract: This cohort study evaluates the feasibility and utility of incorporating comparative gene expression information into the precision medicine framework for difficult-to-treat pediatric and young adult patients with cancer. read more here.
Keywords: young adult; pediatric young; patients cancer; difficult treat ... See more keywords
Incidence, Risk Factors, and Mortality Associated With Second Malignant Neoplasms Among Survivors of Adolescent and Young Adult Cancer
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DOI: 10.1001/jamanetworkopen.2019.5536
Abstract: Key Points Question What are the incidence patterns and risk factors for second malignant neoplasms (SMN) among survivors of adolescent and young adult cancer? Findings This cohort study of 10 574 survivors of adolescent and young… read more here.
Keywords: survivors adolescent; risk; young adult; adult cancer ... See more keywords
Associations Between Mother-Adolescent and Father-Adolescent Relationships and Young Adult Health
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DOI: 10.1001/jamanetworkopen.2023.3944
Abstract: Key Points Question What characteristics of the parent-adolescent relationship are associated with young adult health outcomes? Findings In this cohort study of more than 15 000 adolescents, higher levels of adolescent-reported parental warmth, parent-adolescent communication, time… read more here.
Keywords: young adult; health; associations mother; adolescent ... See more keywords
Age‐related changes in the marmoset gut microbiome
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DOI: 10.1002/ajp.22960
Abstract: The gut microbiome is known to play a significant role in human health but its role in aging remains unclear. The objective of this study was to compare the gut microbiome composition between young adult… read more here.
Keywords: young adult; compared young; marmosets significantly; geriatric marmosets ... See more keywords
Prevalence and correlates of skin examination among ethnically diverse young adult survivors of childhood cancer
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DOI: 10.1002/cam4.5520
Abstract: Skin cancer is the most common secondary malignancy among young adult childhood cancer survivors (YA‐CCS). Skin examination to detect skin cancer early (including melanoma as well as basal or squamous cell skin cancers), both physician‐based… read more here.
Keywords: childhood cancer; young adult; skin examination; cancer ... See more keywords
Accelerated epigenetic aging and myopenia in young adult cancer survivors.
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DOI: 10.1002/cam4.5908
Abstract: BACKGROUND Young adult cancer survivors experience early aging-related morbidities and mortality. Biological aging biomarkers may identify at-risk survivors and increase our understanding of mechanisms underlying this accelerated aging. METHODS Using an observational study design, we… read more here.
Keywords: young adult; age; adult cancer; cancer ... See more keywords
Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging
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DOI: 10.1002/cncr.30857
Abstract: Large epidemiologic studies have reported the premature onset of age‐related conditions, such as ischemic heart disease and diabetes mellitus, in childhood cancer survivors, decades earlier than in their peers. The authors investigated whether young adult… read more here.
Keywords: childhood acute; young adult; adult survivors; lymphoblastic leukemia ... See more keywords
Screening young adult cancer survivors with the PROMIS Depression Short Form (PROMIS‐D‐SF): Comparison with a structured clinical diagnostic interview
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DOI: 10.1002/cncr.32689
Abstract: The current study was conducted to evaluate the Patient‐Reported Outcomes Measurement Information System Depression Short Form (PROMIS‐D‐SF) as a screening measure for young adult cancer survivors (YACS) compared with a structured diagnostic interview. read more here.
Keywords: young adult; adult cancer; short form; depression short ... See more keywords
Accelerated aging among childhood, adolescent, and young adult cancer survivors is evidenced by increased expression of p16INK4a and frailty
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DOI: 10.1002/cncr.33112
Abstract: Cellular senescence, measured by expression of the cell cycle kinase inhibitor p16INK4a, may contribute to accelerated aging in survivors of childhood, adolescent, and young adult cancer. The authors measured peripheral blood T‐lymphocyte p16INK4a expression among… read more here.
Keywords: young adult; accelerated aging; adult cancer; expression ... See more keywords
Psychological distress and associated additional medical expenditures in adolescent and young adult cancer survivors
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DOI: 10.1002/cncr.34064
Abstract: Adolescent and young adult (AYA) cancer survivors experience psychological distress often because of cancer and its treatment. However, no prior studies have evaluated the additional medical expenditures and health care utilization associated with psychological distress… read more here.
Keywords: cancer; psychological distress; cancer survivors; adolescent young ... See more keywords
Posttraumatic stress symptoms and financial toxicity among adolescent and young adult oncology patients and their caregivers at cancer diagnosis
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DOI: 10.1002/cncr.34146
Abstract: Adolescent and young adult oncology (AYAO) patients and caregivers may experience significant psychosocial dysfunction and financial toxicity. Understanding early risk factors is critical to improving survivorship trajectories. read more here.
Keywords: oncology; young adult; patients caregivers; adolescent young ... See more keywords