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   Articles with "ywhaz" as a keyword



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YWHAZ variation causes intellectual disability and global developmental delay with brain malformation

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recommendations! Published in 2022 at "Human Molecular Genetics"

DOI: 10.1093/hmg/ddac210

Abstract: Abstract YWHAZ encodes an adapter protein 14–3-3ζ, which is involved in many signaling pathways that control cellular proliferation, migration and differentiation. It has not been definitely correlated to any phenotype in OMIM. To investigate the… read more here.

Keywords: intellectual disability; ywhaz; disability; developmental delay ... See more keywords
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Epigenetic Silencing of STAT3-Targeted miR-193a, by Constitutive Activation of JAK/STAT Signaling, Leads to Tumor Progression Through Overexpression of YWHAZ in Gastric Cancer

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recommendations! Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.575667

Abstract: Purpose The purpose of this study was to identify genes that were epigenetically silenced by STAT3 in gastric cancer. Methods MBDcap-Seq and expression microarray were performed to identify genes that were epigenetically silenced in AGS… read more here.

Keywords: methylation; gastric cancer; stat3; ywhaz ... See more keywords
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Exploiting Interdata Relationships in Prostate Cancer Proteomes: Clinical Significance of HO-1 Interactors

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recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11020290

Abstract: Prostate cancer (PCa) cells display abnormal expression of proteins resulting in an augmented capacity to resist chemotherapy and colonize distant organs. We have previously shown the anti-tumoral role of heme oxygenase 1 (HO-1) in this… read more here.

Keywords: prostate cancer; ywhaz; exploiting interdata; pca ... See more keywords

Knockdown of tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) enhances tumorigenesis both in vivo and in vitro in bladder cancer

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recommendations! Published in 2018 at "Oncology Reports"

DOI: 10.3892/or.2018.6294

Abstract: Bladder cancer is the most common tumor of the urinary tract. Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ), a gene encoding the 14-3-3ζ protein, has been observed to be frequently amplified in bladder cancer. However,… read more here.

Keywords: cancer; bladder cancer; ywhaz; tyrosine monooxygenase ... See more keywords
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Circ-VPS13C enhances cisplatin resistance in ovarian cancer via modulating miR-106b-5p/YWHAZ axis

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recommendations! Published in 2021 at "Archives of Medical Science"

DOI: 10.5114/aoms/133038

Abstract: Introduction Ovarian cancer (OC) is the malignant tumor with the highest mortality among gynecological cancers. Chemotherapy resistance is a major obstacle to OC therapy. Circular RNAs (circRNAs) play crucial roles in cancer development and chemoresistance.… read more here.

Keywords: circ vps13c; resistance; vps13c; mir 106b ... See more keywords