Practical synthesis of phthalascidin and zalypsis antitumor agents
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DOI: 10.1016/j.tetlet.2021.153498
Abstract: Abstract The first total synthesis of zalypsis and the practical synthesis of phthalascidin (Pt-650) are achieved through the Pictet-Spengler cyclization coupling strategy. The direct iodination of the primary alcohol in trihydroxyl intermediate 26 followed by… read more here.
Keywords: synthesis; zalypsis; synthesis phthalascidin; practical synthesis ... See more keywords