ZAR1 knockdown promotes the differentiation of human neuroblastoma cells by suppression of MYCN expression
Sign Up to like & getrecommendations! Published in 2017 at "Medical Oncology"
DOI: 10.1007/s12032-017-0999-x
Abstract: Although DNA hypermethylation at non-promoter region of the Zygote arrest 1 (ZAR1) gene has been observed in many types of tumor, including neuroblastoma (NB), the role of this gene in tumor development and/or progression is… read more here.
Keywords: mycn expression; zar1; expression; depleted cells ... See more keywords
Two Arabidopsis Receptor-like Cytoplasmic Kinases SZE1 and SZE2 Associate with the ZAR1-ZED1 Complex and Are Required for Effector-Triggered Immunity.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular plant"
DOI: 10.1016/j.molp.2019.03.012
Abstract: Plants utilize intracellular nucleotide-binding leucine-rich repeat domain-containing receptors (NLRs) to recognize pathogen effectors and induce a robust defense response named effector-triggered immunity (ETI). The Arabidopsis NLR protein HOPZ-ACTIVATED RESISTANCE 1 (ZAR1) forms a precomplex with HOPZ-ETI-DEFICIENT… read more here.
Keywords: zed1; sze1 sze2; triggered immunity; zar1 ... See more keywords
Bacterial effectors induce oligomerization of immune receptor ZAR1 in vivo.
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DOI: 10.1016/j.molp.2020.03.004
Abstract: Plants utilize nucleotide-binding (NB), leucine-rich repeat (LRR) receptors (NLRs) to detect pathogen effectors, leading to effector-triggered immunity. The NLR ZAR1 indirectly recognizes the Xanthomonas campestris pv. campestris effector AvrAC and Pseudomonas syingae effector HopZ1a, by… read more here.
Keywords: hopz1a; disease resistance; induce oligomerization; effectors induce ... See more keywords
Analysis of the ZAR1 Immune Complex Reveals Determinants for Immunity and Molecular Interactions1[OPEN]
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DOI: 10.1104/pp.17.00441
Abstract: Deciphering the molecular interactions within the ZAR1-ZED1 immune complex that lead to the induction of plant immunity. Plants depend on innate immunity to prevent disease. Plant pathogenic bacteria, like Pseudomonas syringae and Xanthomonas campestris, use… read more here.
Keywords: immunity; plant; immune complex; zar1 ... See more keywords